San Francisco 49ers vs Houston Texans Predictions & Picks 

San Francisco 49ers vs Houston Texans Predictions


Key Stat: Both teams earned some unexpected victories in the last two weeks 

Tip Reasoning

  • Houston defeated Rams last weekend despite having a couple of big fumbles 
  • Texans are looking for a revenge for January loss to 49ers  
  • At the moment of writing this preview, betting sites are slightly favoring the visitors 


There is some interesting NFL preseason action happening on Thursday night at NRG Stadium where Houston Texans welcome San Francisco 49ers. This is going to be the last exhibition encounter for both sides, as things are getting slightly more serious in seven days. Visitors left extremely positive impression after defeating Vikings in the most recent appearance. All games are live streamed at NFL.com so make sure not to miss the action. 

In terms of the latest lines, betting sites in the US are favoring 49ers to win the match by three and a half points. Houston Texans managed to catch New Orleans Saints off guard and win that friendly encounter 17 to 13 thanks to late touchdown. Jeff Driskel delivered some nice plays, total of 163 yards for two TD’s. 4th quarter was the deciding one last week against Los Angeles Rams, where Texans claimed another surprising victory. 

The most recent head to head duel between these opponents took place in California on 2nd of January 2022. San Francisco claimed comfortable 23-7 victory back then. Truth be told, both teams are looking hot right now with equal chances to win. This said, we are going for the higher +165 line on Texans to win. 

Tip Reasoning

Key Stat: All signs are pointing at direction of another preseason shootout  

  • The current line for points total is 41.5 
  • Texans looked really well offensively against the Rams and Saints 
  • San Francisco scored 36 points in the last two head to head games against Texans which were competitive 

As for the secondary suggestion, the current line for points is set to 41.5. We mentioned above that Texans have been delivering good numbers offensively, scoring total of 41 points in games against two rough opponents. It’s a preseason duel after all and we expect to see a shootout and relaxed approach. 

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